Eclectic Light Company:

For the great majority of Mojave users, its new stringent privacy protection may pass almost unnoticed. If the apps that you run don’t try to access newly-protected private data, you will hardly notice the change. That doesn’t mean to say that the protection is wasted, just that it will get on with doing its job quietly.

If you use third-party apps and other tools which do look in protected folders, or which use restricted features such as controlling other apps using AppleEvents, then you can save yourself a lot of potential trouble with a little planning and preparation, which this article explains.

Things like 1Password, SpamSieve and the like will need to acess this. Thanks to my friend John Welch for the link.